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Last updated: 2014/7/28
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BAX polyclonal antibody

  • Catalog # : PAB0810
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against a synthetic peptide of BAX.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human BAX.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.2% gelatin, 0.1% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Western Blot
  • Western blot detection against Immunogen.
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 581
  • Gene Name:
  • BAX
  • Gene Alias:
  • BCL2L4
  • Gene Description:
  • BCL2-associated X protein
  • Gene Summary:
  • The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq
  • Other Designations:
  • apoptosis regulator BAX
  • Interactome
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