Rabbit polyclonal antibody raised against synthetic peptide of BDNF.
Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to amino acids 129-138 human BDNF.
Sequence:
HSDPARRGEL
Host:
Rabbit
Reactivity:
Human, Rat
Specificity:
Less than 0.1% cross reactivity with mouse NGF, recombinant human NT3 and NT4/5 has been recorded by dot blot analysis.
Form:
Lyophilized
Recommend Usage:
Immunohistochemistry (1:1000-1:2000) ELISA (1:1000-1:2000) Western Blot (1:1000-1:2000) The optimal working dilution should be determined by the end user.
Storage Buffer:
Lyophilized from PBS
Storage Instruction:
Store at 4°C on dry atmosphere. After reconstitution with deionized water, store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq