FCAR (Human) Recombinant Protein
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Specification
Product Description
Human FCAR (P24071, Gln 22 - Asn 227) partial recombinant protein with C-terminal 6His tag expressed in HEK293 cells.
Host
Human
Theoretical MW (kDa)
45-50
Form
Lyophilized
Preparation Method
Mammalian cell (HEK293) expression system
Purification
Ion exchange column and HPLC reverse phase column
Purity
> 90% by SDS-PAGE and HPLC
Endotoxin Level
< 0.1 ng/ug (1 EU/ug)
Storage Buffer
Lyophilized from PBS, pH 7.2
Storage Instruction
Store at -20°C on dry atmosphere.
After reconstitution with deionized water, store at 4°C for one month. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
SDS-PAGE
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Gene Info — FCAR
Entrez GeneID
2204Protein Accession#
P24071Gene Name
FCAR
Gene Alias
CD89
Gene Description
Fc fragment of IgA, receptor for
Omim ID
147045Gene Ontology
HyperlinkGene Summary
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
Other Designations
Fc alpha receptor|IgA Fc receptor|OTTHUMP00000068692|OTTHUMP00000068696|OTTHUMP00000068697|OTTHUMP00000068698
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