Product Browser

Last updated: 2014/4/21
  • Related Product Showcase

Product Compare

Product Compare Cancel   Click this icon to add products to compare list. Select up to 10 products.

Quick Order (Tutorial)

Input Catalog #,
place order here!
Catalog # :
  • Where to buy
  • Choose your location
BIOtech
BULK-new

MME monoclonal antibody, clone CB-Calla

  • Catalog # : MAB8549
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against full length native MME.
  • Immunogen:
  • Native pufiried MME from human B-lineage leukemia cells.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is specific to MME.
  • Form:
  • Liquid
  • Isotype:
  • IgG2b
  • Recommend Usage:
  • Flow cytometry (1 ug/106 cells)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In BBS, pH8.2
  • Storage Instruction:
  • Store at 4°C.
  • Publication Reference
  • Applications
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Flow Cytometry
  • Application Image
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 4311
  • Gene Name:
  • MME
  • Gene Alias:
  • CALLA,CD10,DKFZp686O16152,MGC126681,MGC126707,NEP
  • Gene Description:
  • membrane metallo-endopeptidase
  • Gene Summary:
  • This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. [provided by RefSeq
  • Other Designations:
  • atriopeptidase,common acute lymphocytic leukemia antigen,enkephalinase,membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase),membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10),membrane metallo-endopeptidase
  • RSS
  • YouTube
  • Linkedin
  • Facebook