BSG monoclonal antibody, clone UM-8D6
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Specification
Product Description
Mouse monoclonal antibody raised against native BSG.
Immunogen
Native purified BSG from human T cell line Molt 13.
Host
Mouse
Reactivity
Human
Specificity
This antibody inhibits homotypic aggregation, adhesion to matrix proteins and migation through matrigel.
Form
Liquid
Isotype
IgG1
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In 50 mM sodium phosphate buffer, 100 mM potassium Chloride, 150 mM NaCl, pH 7.5 (0.5 mg/mL gentamicin sulfate)
Storage Instruction
Store at 4°C.
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Applications
Immunohistochemistry (Frozen sections)
Immunoprecipitation
Flow Cytometry
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Gene Info — BSG
Entrez GeneID
682Gene Name
BSG
Gene Alias
5F7, CD147, EMMPRIN, M6, OK, TCSF
Gene Description
basigin (Ok blood group)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. The encoded protein is also a member of the immunoglobulin superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
CD147 antigen|M6 leukocyte activation antigen|OK blood group antigen|basigin|collagenase stimulatory factor|extracellular matrix metalloproteinase inducer
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Interactome
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Disease
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Publication Reference
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The pattern of expression of CD147/neurothelin during human T-cell ontogeny as defined by the monoclonal antibody 8D6.
Kirsch AH, Diaz LA Jr, Bonish B, Antony PA, Fox DA.
Tissue Antigens 1997 Aug; 50(2):147.
Application：Flow Cyt, IP-WB, Human, HSB-2 T cells, CD4+ thymocytes.
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The pattern of expression of CD147/neurothelin during human T-cell ontogeny as defined by the monoclonal antibody 8D6.
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