IL6 monoclonal antibody, clone MQ2-39C3 (Biotin)
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Specification
Product Description
Rat monoclonal antibody raised against recombinant IL6.
Immunogen
Recombinant protein corresponding to human IL6.
Host
Rat
Reactivity
Human
Specificity
human Interleukin-6 (IL-6)1-3. This is a neutralizing antibody.
Form
Liquid
Conjugation
Biotin
Isotype
IgG2a, kappa
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — IL6
Entrez GeneID
3569Gene Name
IL6
Gene Alias
BSF2, HGF, HSF, IFNB2, IL-6
Gene Description
interleukin 6 (interferon, beta 2)
Gene Ontology
HyperlinkGene Summary
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq
Other Designations
interleukin 6
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Interactome
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Pathway
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Disease
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Publication Reference
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The international standard for interleukin-6. Evaluation in an international collaborative study.
Gaines Das RE, Poole S.
Journal of Immunological Methods 1993 Apr; 160(2):147.
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Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples.
Abrams JS, Roncarolo MG, Yssel H, Andersson U, Gleich GJ, Silver JE.
Immunological Reviews 1992 Jun; 127:5.
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The international standard for interleukin-6. Evaluation in an international collaborative study.
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