CSF2 monoclonal antibody, clone BVD2-21C11 (Biotin)
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Rat monoclonal antibody raised against recombinant CSF2.
Immunogen
Recombinant protein corresponding to human CSF2.
Host
Rat
Reactivity
Human, Macaque
Specificity
human granulocyte/macrophage-colony stimulating factor (GM-CSF)1-4 The BVD2-21C11 antibody has been reported to cross react with GM-CSF from Rhesus monkey. (This is a neutralizing antibody.).
Form
Liquid
Conjugation
Biotin
Isotype
IgG2a
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Enzyme-linked Immunoabsorbent Assay
-
Gene Info — CSF2
Entrez GeneID
1437Gene Name
CSF2
Gene Alias
GMCSF, MGC131935, MGC138897
Gene Description
colony stimulating factor 2 (granulocyte-macrophage)
Omim ID
138960Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq
Other Designations
colony stimulating factor 2|granulocyte-macrophage colony stimulating factor|molgramostin|sargramostim
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples.
Abrams JS, Roncarolo MG, Yssel H, Andersson U, Gleich GJ, Silver JE.
Immunological Reviews 1992 Jun; 127:5.
-
Granulocyte/macrophage colony-stimulating factor and interleukin 3 release from human peripheral blood eosinophils and neutrophils.
Kita H, Ohnishi T, Okubo Y, Weiler D, Abrams JS, Gleich GJ.
The Journal of Experimental Medicine 1991 Sep; 174(3):745.
-
Host-reactive CD4+ and CD8+ T cell clones isolated from a human chimera produce IL-5, IL-2, IFN-gamma and granulocyte/macrophage-colony-stimulating factor but not IL-4.
Bacchetta R, de Waal Malefijt R, Yssel H, Abrams J, de Vries JE, Spits H, Roncarolo MG.
The Journal of Immunology 1990 Feb; 144(3):902.
-
Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com