CCL2 monoclonal antibody, clone 1A7B8
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Recombinant protein)
Western bot analysis using CCL2 monoclonal antibody, clone 1A7B8 (Cat # MAB5536) against truncated CCL2 recombinant protein.
-
Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant CCL2.
Immunogen
Recombinant protein corresponding to human CCL2.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG1, kappa
Recommend Usage
Western Blot (1:500-1:1000)
ELISA (1:1000-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Recombinant protein)
Western bot analysis using CCL2 monoclonal antibody, clone 1A7B8 (Cat # MAB5536) against truncated CCL2 recombinant protein.Enzyme-linked Immunoabsorbent Assay
-
Gene Info — CCL2
Entrez GeneID
6347Gene Name
CCL2
Gene Alias
GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, MGC9434, SCYA2, SMC-CF
Gene Description
chemokine (C-C motif) ligand 2
Gene Ontology
HyperlinkGene Summary
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. [provided by RefSeq
Other Designations
monocyte chemoattractant protein-1|monocyte chemotactic and activating factor|monocyte chemotactic protein 1, homologous to mouse Sig-je|monocyte secretory protein JE|small inducible cytokine A2|small inducible cytokine A2 (monocyte chemotactic protein 1,
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Assignment of the human small inducible cytokine A2 gene, SCYA2 (encoding JE or MCP-1), to 17q11.2-12: evolutionary relatedness of cytokines clustered at the same locus.
Rollins BJ, Morton CC, Ledbetter DH, Eddy RL Jr, Shows TB.
Genomics 1991 Jun; 10(2):489.
-
Human monocyte chemoattractant protein-1 (MCP-1).
Yoshimura T, Leonard EJ.
Adv Exp Med Biol 1991 Jan; 305.
-
Human monocyte chemoattractant protein-1 (MCP-1). Full-length cDNA cloning, expression in mitogen-stimulated blood mononuclear leukocytes, and sequence similarity to mouse competence gene JE.
Yoshimura T, Yuhki N, Moore SK, Appella E, Lerman MI, Leonard EJ.
FEBS Letters 1989 Feb; 244(2):487.
-
Assignment of the human small inducible cytokine A2 gene, SCYA2 (encoding JE or MCP-1), to 17q11.2-12: evolutionary relatedness of cytokines clustered at the same locus.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com