Mouse monoclonal antibody raised against native CD9.
Immunogen:
Native purified CD9 from Pre-B cell line NALM-6.
Host:
Mouse
Theoretical MW (kDa):
24
Reactivity:
Human
Specificity:
This antibody recognizes an epitope on second extracellular domain (EC2) of CD9 antigen, a 24 KDa transmembrane protein expressed on platelets, monocytes, pre-B lymphocytes, granulocytes and activated T lymphocytes.
Form:
Liquid
Conjugation:
FITC
Isotype:
IgG1
Recommend Usage:
Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension) The optimal working dilution should be determined by the end user.
Storage Buffer:
In PBS (0.2% BSA, 15 mM sodium azide)
Storage Instruction:
Store in the dark at 4°C. Do not freeze. Avoid prolonged exposure to light. Aliquot to avoid repeated freezing and thawing.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Surface staining of NALM-6 (human pre-B cell leukemia cell line) with CD9 monoclonal antibody, clone MEM-61 (FITC) (Cat # MAB4566). Total viable cells were used for analysis.
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It can modulate cell adhesion and migration and also trigger platelet activation and aggregation. In addition, the protein appears to promote muscle cell fusion and support myotube maintenance. [provided by RefSeq
Other Designations:
5H9 antigen,CD9 antigen,CD9 antigen (p24),OTTHUMP00000041574,OTTHUMP00000041576,antigen defined by monoclonal antibody 602-29,growth-inhibiting gene 2 protein,leukocyte antigen MIC3,motility related protein,motility related protein-1,p24 antigen