PCNA monoclonal antibody, clone k1A3
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant PCNA.
Immunogen
Recombinant protein corresponding to amino acids 1-261 of human PCNA.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Isotype
IgG3, kappa
Recommend Usage
ELISA
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (10% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
Western blot analysis of Lane 1: HeLa cell lysate, Lane 2: NIH3T3 cell lysate.Enzyme-linked Immunoabsorbent Assay
-
Gene Info — PCNA
Entrez GeneID
5111Protein Accession#
NP_002583Gene Name
PCNA
Gene Alias
MGC8367
Gene Description
proliferating cell nuclear antigen
Omim ID
176740Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq
Other Designations
DNA polymerase delta auxiliary protein|OTTHUMP00000030189|OTTHUMP00000030190|cyclin
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
PCNA, the maestro of the replication fork.
Moldovan GL, Pfander B, Jentsch S.
Cell 2007 May; 129(4):665.
-
Molecular cloning of cDNA coding for rat proliferating cell nuclear antigen (PCNA)/cyclin.
Matsumoto K, Moriuchi T, Koji T, Nakane PK.
The EMBO Journal 1987 Mar; 6(3):637.
-
PCNA, the maestro of the replication fork.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com