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CTSD monoclonal antibody, clone AF5H4   

  • Catalog # : MAB2718
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  • 100 uL
  • USD $ 319
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    Phone : +1-909-992-0619 (new)
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant CTSD.
  • Immunogen:
  • Recombinant His fusion protein corresponding to human CTSD.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Ammonium sulfate precipitation
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Immunoblot analysis of cell lysates.
    Lane 1 : MCF-7 cell lysate.
    Lnae 2 : HepG2 cell lysate.
    Lane 3 : SK-BR-3 cell lysate.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1509
  • Gene Name:
  • CTSD
  • Gene Alias:
  • CLN10,CPSD,MGC2311
  • Gene Description:
  • cathepsin D
  • Gene Summary:
  • This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease. [provided by RefSeq
  • Other Designations:
  • lysosomal aspartyl peptidase,lysosomal aspartyl protease
  • Gene Pathway
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