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IL10 monoclonal antibody, clone SPM464

  • Catalog # : MAB2539
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  • Specification
  • Product Description:
  • Rat monoclonal antibody raised against synthetic peptide of IL10.
  • Immunogen:
  • A synthetic peptide corresponding to human IL10.
  • Host:
  • Rat
  • Theoretical MW (kDa):
  • 15, 19
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (0.1-0.2 ug/mL)
    ELISA (0.01-0.1 ug/mL)
    Immunoprecipitation (2-5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (10% Proclin300)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing. Upon initial thawing, apportion into working aliquots and store at -80°C for up to six months.
  • Applications
  • Western Blot
  • Immunoprecipitation
  • ELISA
  • Application Image
  • Western Blot
  • Immunoprecipitation
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3586
  • Gene Name:
  • IL10
  • Gene Alias:
  • CSIF,IL-10,IL10A,MGC126450,MGC126451,TGIF
  • Gene Description:
  • interleukin 10
  • Gene Summary:
  • The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. [provided by RefSeq
  • Other Designations:
  • cytokine synthesis inhibitory factor
  • Interactome
  • Related Disease
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