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Last updated: 2014/4/14
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NF1 monoclonal antibody, clone McNFn27a

  • Catalog # : MAB2305
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of NF1.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 27-41 of human NF1.
  • Host:
  • Mouse
  • Reactivity:
  • Guinea pig, Human, Mouse, Rat
  • Specificity:
  • This antibody is specific to full-length or truncated forms of neurofibromin.
  • Form:
  • Liquid
  • Isotype:
  • IgG1, kappa
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (2-5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C for short term. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis of NF1 in Schwann cells from embryonic knockout mice, adult human nerves and neonatal rat nerves with NF1 monoclonal antibody, clone McNFn27a (Cat # MAB2305).
  • Immunoprecipitation
  • Application Image
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 4763
  • Gene Name:
  • NF1
  • Gene Alias:
  • DKFZp686J1293,FLJ21220,NFNS,VRNF,WSS
  • Gene Description:
  • neurofibromin 1
  • Gene Summary:
  • This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq
  • Other Designations:
  • neurofibromin
  • Gene Pathway
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