BIRC5 monoclonal antibody, clone 2H5H2
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More Files
- More Functions
Western Blot (Transfected lysate)
Western blot analysis using BIRC5 monoclonal antibody, clone 2H5H2 (Cat # MAB10414) against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY BIRC5 cDNA (2).
Western Blot
Western blot analysis using BIRC5 monoclonal antibody, clone 2H5H2 (Cat # MAB10414) against full-length BIRC5 recombinant protein (1) and full-length BIRC5-GFP transfected COS-7 cell lysate (2).
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant BIRC5.
Immunogen
Recombinant protein corresponding to human BIRC5.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis using BIRC5 monoclonal antibody, clone 2H5H2 (Cat # MAB10414) against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY BIRC5 cDNA (2).Western Blot
Western blot analysis using BIRC5 monoclonal antibody, clone 2H5H2 (Cat # MAB10414) against full-length BIRC5 recombinant protein (1) and full-length BIRC5-GFP transfected COS-7 cell lysate (2).Enzyme-linked Immunoabsorbent Assay
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Gene Info — BIRC5
Entrez GeneID
332Gene Name
BIRC5
Gene Alias
API4, EPR-1
Gene Description
baculoviral IAP repeat-containing 5
Omim ID
603352Gene Ontology
HyperlinkGene Summary
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq
Other Designations
apoptosis inhibitor 4|baculoviral IAP repeat-containing protein 5|survivin variant 3 alpha
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Interactome
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Pathway
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Disease
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