MAP3K7IP2 monoclonal antibody, clone 3B5
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More Files
- More Functions
Western Blot (Transfected lysate)
Western blot analysis using MAP3K7IP2 monoclonal antobody, clone 3B5 (Cat # MAB10330) against HEK293 (1) and MAP3K7IP2-hIgGFc transfected HEK293 (2) cell lysate.
Flow Cytometry
Flow cytometric analysis of HL-60 cells using MAP3K7IP2 monoclonal antobody, clone 3B5 (Cat # MAB10330) (green) and negative control (purple).
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant MAP3K7IP2.
Immunogen
Recombinant protein corresponding to human MAP3K7IP2.
Host
Mouse
Theoretical MW (kDa)
80
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Flow cytometry (1:200-1:400)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis using MAP3K7IP2 monoclonal antobody, clone 3B5 (Cat # MAB10330) against HEK293 (1) and MAP3K7IP2-hIgGFc transfected HEK293 (2) cell lysate.Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
Flow cytometric analysis of HL-60 cells using MAP3K7IP2 monoclonal antobody, clone 3B5 (Cat # MAB10330) (green) and negative control (purple). -
Gene Info — MAP3K7IP2
Entrez GeneID
23118Gene Name
MAP3K7IP2
Gene Alias
FLJ21885, KIAA0733, TAB2
Gene Description
mitogen-activated protein kinase kinase kinase 7 interacting protein 2
Omim ID
605101Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. [provided by RefSeq
Other Designations
OTTHUMP00000017388|OTTHUMP00000040125|TAK1-binding protein 2
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Interactome
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Pathway
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Disease
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