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ERBB2 (Human) ELISA Kit

  • Catalog # : KA0118
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  • Specification
  • Product Description:
  • ERBB2 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human sHER-2.
  • Calibration Range:
  • 0.16 to 10 ng/mL
  • Limit of Detection:
  • 0.06 ng/mL
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Standard curve

    QC Testing of KA0118
    The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
  • Storage Instruction:
  • Store the kit at 4°C.
  • Suitable Sample:
  • Amniotic Fluid, Cell Culture Supernatant, Plasma (EDTA, Heparin), Serum
  • Sample Volume:
  • 100 uL (1:20 prediluted)
  • Label:
  • HRP-conjugate
  • Detection Method:
  • Colorimetric
  • Intra-Assay:
  • 1.90%
  • Inter-Assay:
  • 5.80%
  • Spiking Recovery:
  • 89.00%
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Quantification
  • Application Image
  • Quantification
  • Gene Information
  • Entrez GeneID:
  • 2064
  • Gene Name:
  • ERBB2
  • Gene Alias:
  • CD340,HER-2,HER-2/neu,HER2,NEU,NGL,TKR1
  • Gene Description:
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
  • Gene Summary:
  • This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq
  • Other Designations:
  • c-erb B2/neu protein,erbB-2,herstatin,neuroblastoma/glioblastoma derived oncogene homolog,v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog)
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