AADAT polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (37.11 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant AADAT.
Immunogen
AADAT (NP_057312, 326 a.a. ~ 425 a.a) partial recombinant protein with GST tag.
Sequence
YSNQKDAILAAADKWLTGLAEWHVPAAGMFLWIKVKGINDVKELIEEKAVKMGVLMLPGNAFYVDSSAPSPYLRASFSSASPEQMDVAFQVLAQLIKESL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (72); Rat (71)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — AADAT
Entrez GeneID
51166GeneBank Accession#
NM_016228Protein Accession#
NP_057312Gene Name
AADAT
Gene Alias
KAT2, KATII
Gene Description
aminoadipate aminotransferase
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Two alternative transcripts encoding the same isoform have been identified, however, additional alternative transcripts and isoforms may exist. [provided by RefSeq
Other Designations
L kynurenine/alpha aminoadipate aminotransferase|L-kynurenine/alpha-aminoadipate aminotransferase|alpha-aminoadipate aminotransferase|kynurenine aminotransferase II
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Interactome
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Pathway
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Publication Reference
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Characterization of the Kynurenine Pathway in Human Neurons.
Guillemin GJ, Cullen KM, Lim CK, Smythe GA, Garner B, Kapoor V, Takikawa O, Brew BJ.
Journal of Neuroscience 2007 Nov; 27(47):12884.
Application：IF, Human, Human neurons, SK-N-SH cells.
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Characterization of the Kynurenine Pathway in Human Neurons.
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