TNRC6A monoclonal antibody (M05), clone 2A10
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More Files
- More Functions
Western Blot detection against Immunogen (37.00 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant TNRC6A.
Immunogen
TNRC6A (NP_055309, 254 a.a. ~ 353 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MDADSASSSESERNITIMASGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSSN
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94); Rat (93)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.00 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — TNRC6A
Entrez GeneID
27327GeneBank Accession#
NM_014494Protein Accession#
NP_055309Gene Name
TNRC6A
Gene Alias
CAGH26, DKFZp666E117, FLJ22043, GW1, GW182, KIAA1460, MGC75384, TNRC6
Gene Description
trinucleotide repeat containing 6A
Omim ID
610739Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing. [provided by RefSeq
Other Designations
CAG repeat protein 26|EDIE|GW182 autoantigen|OTTHUMP00000122485|glycine-tryptophan protein of 182 kDa|trinucleotide repeat-containing gene 6A
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Interactome
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