KRT23 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human KRT23 full-length ORF ( AAH28356, 1 a.a. - 422 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MNSGHSFSQTPSASFHGAGGGWGRPRSFPRAPTVHGGAGGARISLSFTTRSCPPPGGSWGSGRSSPLLGGNGKATMQNLNDRLASYVEKVRALEEANMKLESRILKWHQQRDPGSKKDYSQYEENITHLQEQIVDGKMTNAQIILLIDNARMAVDDFNLKYENEHSFKKDLEIEVEGLRRTLDNLTIVTTDLEQEVEGMRKELILMKKHHEQEMEKHHVPSDFNVNVKVDTGPREDLIKVLEDMRQEYELIIKKKHRDLDTWYKEQSAAMSQEAASPATVQSRQGDIHELKRTFQALEIDLQTQYSTKSALENMLSETQSRYSCKLQDMQEIISHYEEELTQLRHELERQNNEYQVLLGIKTHLEKEITTYRRLLEGESEGTREESKSSMKVFATPKIKAITQETINGRLVLCQVNEIQKHA
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
72.16
Interspecies Antigen Sequence
Mouse (78); Rat (79)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — KRT23
Entrez GeneID
25984GeneBank Accession#
BC028356Protein Accession#
AAH28356Gene Name
KRT23
Gene Alias
CK23, DKFZp434G032, HAIK1, K23, MGC26158
Gene Description
keratin 23 (histone deacetylase inducible)
Omim ID
606194Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq
Other Designations
cytokeratin 23|histone deacetylase inducible keratin 23|hyperacetylation-inducible type I keratin|keratin 23|keratin, type I cytoskeletal 23|type I intermediate filament cytokeratin
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Interactome
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Disease
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Publication Reference
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Identification of putative immunologic targets for colon cancer prevention based on conserved gene expression from pre-invasive to malignant lesions.
Broussard EK, Kim R, Wiley JC, Marquez JP, Annis JE, Pritchard D, Disis ML.
Cancer Prevention Research (Philadelphia, Pa.) 2013 Jul; 6(7):666.
Application：WB, WB-Tr, Human, Serum, HCT116, LoVo, RKO, SW48, FET, SW480 cells.
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Identification of putative immunologic targets for colon cancer prevention based on conserved gene expression from pre-invasive to malignant lesions.
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