MAP3K7IP2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
MAP3K7IP2 transfected lysate.
Western Blot
Lane 1: MAP3K7IP2 transfected lysate ( 76.5 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-MAP3K7IP2 full-length
Host
Human
Theoretical MW (kDa)
76.5
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-MAP3K7IP2 antibody (H00023118-B01) by Western Blots.
SDS-PAGE Gel
MAP3K7IP2 transfected lysate.
Western Blot
Lane 1: MAP3K7IP2 transfected lysate ( 76.5 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — MAP3K7IP2
Entrez GeneID
23118GeneBank Accession#
NM_015093Protein Accession#
NP_055908Gene Name
MAP3K7IP2
Gene Alias
FLJ21885, KIAA0733, TAB2
Gene Description
mitogen-activated protein kinase kinase kinase 7 interacting protein 2
Omim ID
605101Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. [provided by RefSeq
Other Designations
OTTHUMP00000017388|OTTHUMP00000040125|TAK1-binding protein 2
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Interactome
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Pathway
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Disease
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