This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity:
Human
Quality Control Testing:
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of MAP3K7IP2 transfected lysate using rabbit polyclonal anti-MAP3K7IP2 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse polyclonal anti-MAP3K7IP2.
Supplied Product:
Antibody pair set content: 1. Antibody pair for IP: rabbit polyclonal anti-MAP3K7IP2 (300 ul) 2. Antibody pair for WB: mouse polyclonal anti-MAP3K7IP2 (50 ul)
Storage Instruction:
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. [provided by RefSeq
Other Designations:
OTTHUMP00000017388,OTTHUMP00000040125,TAK1-binding protein 2