CUGBP1 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-CUGBP1 full-length
Host
Human
Theoretical MW (kDa)
51.6
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-CUGBP1 antibody (H00010658-B01) by Western Blots.
SDS-PAGE Gel
CUGBP1 transfected lysate.
Western Blot
Lane 1: CUGBP1 transfected lysate ( 51.6 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — CUGBP1
Entrez GeneID
10658GeneBank Accession#
NM_198700Protein Accession#
NP_941989Gene Name
CUGBP1
Gene Alias
BRUNOL2, CUG-BP, CUGBP, NAB50, hNab50
Gene Description
CUG triplet repeat, RNA binding protein 1
Omim ID
601074Gene Ontology
HyperlinkGene Summary
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
CUG RNA-binding protein|CUG triplet repeat, RNA-binding protein 1|bruno-like 2|nuclear polyadenylated RNA-binding protein, 50-kD
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