OLIG2 monoclonal antibody (M05), clone 2A8
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More Files
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Specifications
Product Description
Mouse monoclonal antibody raised against a full length recombinant OLIG2.
Immunogen
OLIG2 (NP_005797, 2 a.a. ~ 78 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
DSDASLVSSRPSSPEPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCPPELSAELRGAMGSAGAHPGDKLGGSGFKSS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (34.47 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of OLIG2 expression in transfected 293T cell line by OLIG2 monoclonal antibody (M05), clone 2A8.
Lane 1: OLIG2 transfected lysate(32.4 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Immunoprecipitation
Immunoprecipitation of OLIG2 transfected lysate using anti-OLIG2 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with OLIG2 MaxPab rabbit polyclonal antibody.ELISA
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Gene Info — OLIG2
Entrez GeneID
10215GeneBank Accession#
NM_005806Protein Accession#
NP_005797Gene Name
OLIG2
Gene Alias
BHLHB1, OLIGO2, PRKCBP2, RACK17, bHLHe19
Gene Description
oligodendrocyte lineage transcription factor 2
Omim ID
606386Gene Ontology
HyperlinkGene Summary
This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq
Other Designations
OTTHUMP00000067569|OTTHUMP00000067570|basic domain, helix-loop-helix protein, class B, 1|human protein kinase C-binding protein RACK17|oligodendrocyte-specific bHLH transcription factor 2|protein kinase C binding protein 2
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Interactomes
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Diseases
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