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FADD (Human) Matched Antibody Pair

  • Catalog # : H00008772-AP11
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  • Specification
  • Product Description:
  • This antibody pair set comes with matched antibody pair to detect and quantify protein level of human FADD.
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Standard curve using recombinant protein ( H00008772-P01 ) as an analyte.

    QC Testing of H00008772-AP11
    Sandwich ELISA detection sensitivity ranging from 10 ng/ml to 100 ng/ml.
  • Supplied Product:
  • Antibody pair set content:
    1. Capture antibody: rabbit MaxPab® affinity purified polyclonal anti-FADD (100 ug)
    2. Detection antibody: mouse monoclonal anti-FADD, IgG1 Lambda (20 ug)
    *Reagents are sufficient for at least 3-5 x 96 well plates using recommended protocols.
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Applications
  • Application Image
  • ELISA Pair (Recombinant protein)
  • Gene Information
  • Entrez GeneID:
  • 8772
  • Gene Name:
  • FADD
  • Gene Alias:
  • GIG3,MGC8528,MORT1
  • Gene Description:
  • Fas (TNFRSF6)-associated via death domain
  • Gene Summary:
  • The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq
  • Other Designations:
  • Fas-associated via death domain,Fas-associating death domain-containing protein,Fas-associating protein with death domain,growth-inhibiting gene 3 protein,mediator of receptor-induced toxicity
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