YWHAE polyclonal antibody (A01)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length recombinant YWHAE.
Immunogen
YWHAE (AAH00179, 1 a.a. ~ 255 a.a) full-length recombinant protein with GST tag.
Sequence
MDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVFYYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGDGEEQNKEALQDVEDENQ
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (54.16 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — YWHAE
Entrez GeneID
7531GeneBank Accession#
BC000179Protein Accession#
AAH00179Gene Name
YWHAE
Gene Alias
14-3-3E, FLJ45465, KCIP-1, MDCR, MDS
Gene Description
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
Gene Ontology
HyperlinkGene Summary
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq
Other Designations
14-3-3 epsilon|mitochondrial import stimulation factor L subunit|protein kinase C inhibitor protein-1|tyrosine 3/tryptophan 5 -monooxygenase activation protein, epsilon polypeptide
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Interactome
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Pathway
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Disease
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Publication Reference
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Veränderungen des pulmonalen Proteoms in der experimentellen Herzinsuffizienz.
Sarah Hierl.
Thesis for: doctoral 2015 Sep; 1.
Application:WB-Ti, Rabbit, Human pulmonary tissue specimens.
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Veränderungen des pulmonalen Proteoms in der experimentellen Herzinsuffizienz.
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