TACR1 (Human) Recombinant Protein (Q02)
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More Files
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Specification
Product Description
Human TACR1 partial ORF ( NP_001049.1, 309 a.a. - 407 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
NDRFRLGFKHAFRCCPFISAGDYEGLEMKSTRYLQTQGSVYKVSRLETTISTVVGAHEEEPEDGPKATPSSLDLTSNCSSRSDSKTMTESFSFSSNVLS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.63
Interspecies Antigen Sequence
Mouse (91); Rat (92)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — TACR1
Entrez GeneID
6869GeneBank Accession#
NM_001058Protein Accession#
NP_001049.1Gene Name
TACR1
Gene Alias
NK1R, NKIR, SPR, TAC1R
Gene Description
tachykinin receptor 1
Omim ID
162323Gene Ontology
HyperlinkGene Summary
This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P. [provided by RefSeq
Other Designations
NK-1 receptor|neurokinin 1 receptor|tachykinin 1 receptor (substance P receptor, neurokinin 1 receptor)|tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor)
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Interactome
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Pathway
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Disease
- Alcoholism
- Anorexia Nervosa
- Asthma
- Bipolar Disorder
- Bulimia
- Chronic Disease
- Constipation
- Cough
- Endometriosis
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