This gene encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele. [provided by RefSeq
Other Designations:
2',5'-oligoisoadenylate synthetase-dependent,OTTHUMP00000033148,interferon-induced 2-5A-dependent RNase,ribonuclease 4,ribonuclease L