Product Browser

Last updated: 2014/7/7

Product Compare

Product Compare Cancel   Click this icon to add products to compare list. Select up to 10 products.

Quick Order (Tutorial)

Input Catalog #,
place order here!
Catalog # :
  • Where to buy
  • Choose your location

MAPK8 Validated Chimera RNAi

  • Catalog # : H00005599-R01V
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Homo sapiens mitogen-activated protein kinase 8 (MAPK8), transcript variant 1, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_002750
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown (Antibody validated)
  • RNAi Knockdown (Antibody validated)
  • Western blot analysis of MAPK8 over-expressed 293 cell line, cotransfected with MAPK8 Validated Chimera RNAi ( Cat # H00005599-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with MAPK8 monoclonal antibody (M11) clone 2F11 (Cat # H00005599-M11 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
  • Protocol Download
  • Application Image
  • RNAi Knockdown (Antibody validated)
  • RNAi Knockdown (Antibody validated)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 5599
  • Gene Name:
  • MAPK8
  • Gene Alias:
  • JNK,JNK1,JNK1A2,JNK21B1/2,PRKM8,SAPK1
  • Gene Description:
  • mitogen-activated protein kinase 8
  • Gene Summary:
  • The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
  • Other Designations:
  • JNK1 alpha protein kinase,JNK1 beta protein kinase,JUN N-terminal kinase,OTTHUMP00000019552,OTTHUMP00000019555,OTTHUMP00000019556,OTTHUMP00000019558,c-Jun N-terminal kinase 1,mitogen-activated protein kinase 8 isoform JNK1 alpha1,mitogen-activated protein
  • Interactome
  • RSS
  • YouTube
  • Linkedin
  • Facebook