PPT1 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human PPT1 protein.
Immunogen
PPT1 (NP_000301.1, 1 a.a. ~ 306 a.a) full-length human protein.
Sequence
MASPGCLWLLAVALLPWTCASRALQHLDPPAPLPLVIWHGMGDSCCNPLSMGAIKKMVEKKIPGIYVLSLEIGKTLMEDVENSFFLNVNSQVTTVCQALAKDPKLQQGYNAMGFSQGGQFLRAVAQRCPSPPMINLISVGGQHQGVFGLPRCPGESSHICDFIRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMALKKFVMVKFLNDSIVDPVDSEWFGFYRSGQAKETIPLQETSLYTQDRLGLKEMDNAGQLVFLATEGDHLQLSEEWFYAHIIPFLG
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PPT1 MaxPab polyclonal antibody. Western Blot analysis of PPT1 expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of PPT1 expression in transfected 293T cell line (H00005538-T01) by PPT1 MaxPab polyclonal antibody.
Lane 1: PPT1 transfected lysate(33.66 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of purified MaxPab antibody to PPT1 on formalin-fixed paraffin-embedded human salivary gland. [antibody concentration 3 ug/ml] -
Gene Info — PPT1
Entrez GeneID
5538GeneBank Accession#
NM_000310Protein Accession#
NP_000301.1Gene Name
PPT1
Gene Alias
CLN1, INCL, PPT
Gene Description
palmitoyl-protein thioesterase 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene
Other Designations
OTTHUMP00000004836|ceroid-palmitoyl-palmitoyl-protein thioesterase 1|palmitoyl-protein hydrolase 1
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