PDCD1 purified MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human PDCD1 protein.
Immunogen
PDCD1 (AAH74740.1, 1 a.a. ~ 288 a.a) full-length human protein.
Sequence
MQIPQAPWPVVWAVLQLGWRPGWFLDSPDRPWNPPTFSPALLVVTEGDNATFTCSFSNTSESFVLNWYRMSPSNQTDKLAAFPEDRSQPGQDCRFRVTQLPNGRDFHMSVVRARRNDSGTYLCGAISLAPKAQIKESLRAELRVTERRAEVPTAHPSPSPRPAGQFQTLVVGVVGGLLGSLVLLVWVLAVICSRAARGTIGARRTGQPLKEDPSAVPVFSVDYGELDFQWREKTPEPPVPCVPEQTEYATIVFPSGMGTSSPARRGSADGPRSAQPLRPEDGHCSWPL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (59); Rat (61)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PDCD1 MaxPab polyclonal antibody. Western Blot analysis of PDCD1 expression in human stomach.Western Blot (Cell lysate)
PDCD1 MaxPab polyclonal antibody. Western Blot analysis of PDCD1 expression in HeLa.Western Blot (Transfected lysate)
Western Blot analysis of PDCD1 expression in transfected 293T cell line (H00005133-T01) by PDCD1 MaxPab polyclonal antibody.
Lane 1: PDCD1 transfected lysate(31.68 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PDCD1
Entrez GeneID
5133GeneBank Accession#
BC074740Protein Accession#
AAH74740.1Gene Name
PDCD1
Gene Alias
CD279, PD1, SLEB2, hPD-1, hPD-l
Gene Description
programmed cell death 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq
Other Designations
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