SERPINE1 MaxPab rabbit polyclonal antibody (D01)
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More Files
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Specifications
Product Description
Rabbit polyclonal antibody raised against a full-length human SERPINE1 protein.
Immunogen
SERPINE1 (NP_000593.1, 1 a.a. ~ 402 a.a) full-length human protein.
Sequence
MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP
Host
Rabbit
Reactivity
Human, Mouse
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
SERPINE1 MaxPab rabbit polyclonal antibody. Western Blot analysis of SERPINE1 expression in mouse liver.Western Blot (Transfected lysate)
Western Blot analysis of SERPINE1 expression in transfected 293T cell line (H00005054-T02) by SERPINE1 MaxPab polyclonal antibody.
Lane 1: SERPINE1 transfected lysate(45.1 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of SERPINE1 transfected lysate using anti-SERPINE1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with SERPINE1 purified MaxPab mouse polyclonal antibody (B01P) (H00005054-B01P). -
Gene Info — SERPINE1
Entrez GeneID
5054GeneBank Accession#
NM_000602Protein Accession#
NP_000593.1Gene Name
SERPINE1
Gene Alias
PAI, PAI-1, PAI1, PLANH1
Gene Description
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Omim ID
173360Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
plasminogen activator inhibitor, type I|plasminogen activator inhibitor-1|serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
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Interactomes
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Pathways
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Diseases
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