Products

Western Blot (Tissue lysate)

Western Blot (Tissue lysate)

Western Blot (Cell lysate)

Western Blot (Transfected lysate)

Immunoprecipitation

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

MMP3

Gene Alias

CHDS6, MGC126102, MGC126103, MGC126104, MMP-3, SL-1, STMY, STMY1, STR1

Gene Description

matrix metallopeptidase 3 (stromelysin 1, progelatinase)

Omim ID

Gene Ontology

Gene Summary

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq

Other Designations

matrix metalloproteinase 3|matrix metalloproteinase 3 (stromelysin 1, progelatinase)|progelatinase|proteoglycanase|stromelysin 1|transin-1