KCNJ3 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human KCNJ3 peptide using ARM Technology.
Immunogen
A synthetic peptide of human KCNJ3 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human KCNJ3 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — KCNJ3
Entrez GeneID
3760GeneBank Accession#
KCNJ3Gene Name
KCNJ3
Gene Alias
GIRK1, KGA, KIR3.1
Gene Description
potassium inwardly-rectifying channel, subfamily J, member 3
Omim ID
601534Gene Ontology
HyperlinkGene Summary
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex. [provided by RefSeq
Other Designations
G protein-activated inward rectifier potassium channel 1|inward rectifier K+ channel KIR3.1|potassium inwardly-rectifying channel J3
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