IL1B MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Tissue lysate)
IL1B MaxPab rabbit polyclonal antibody. Western Blot analysis of IL1B expression in mouse testis.
Western Blot (Transfected lysate)
Western Blot analysis of IL1B expression in transfected 293T cell line (H00003553-T01) by IL1B MaxPab polyclonal antibody.
Lane 1: IL1B transfected lysate(30.7 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of IL1B transfected lysate using anti-IL1B MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with IL1B MaxPab mouse polyclonal antibody (B01) (H00003553-B01).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human IL1B protein.
Immunogen
IL1B (AAH08678.1, 1 a.a. ~ 269 a.a) full-length human protein.
Sequence
MAEVPELASEMMAYYSGNEDDLFFEADGPKQMKCSFQDLDLCPLDGGIQLRISDHHYSKGFRQAASVVVAMDKLRKMLVPCPQTFQENDLSTFFPFIFEEEPIFFDTWDNEAYVHDAPVRSLNCTLRDSQQKSLVMSGPYELKALHLQGQDMEQQVVFSMSFVQGEESNDKIPVALGLKEKNLYLSCVLKDDKPTLQLESVDPKNYPKKKMEKRFVFNKIEINNKLEFESAQFPNWYISTSQAENMPVFLGGTKGGQDITDFTMQFVSS
Host
Rabbit
Reactivity
Human, Mouse
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
IL1B MaxPab rabbit polyclonal antibody. Western Blot analysis of IL1B expression in mouse testis.Western Blot (Transfected lysate)
Western Blot analysis of IL1B expression in transfected 293T cell line (H00003553-T01) by IL1B MaxPab polyclonal antibody.
Lane 1: IL1B transfected lysate(30.7 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of IL1B transfected lysate using anti-IL1B MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with IL1B MaxPab mouse polyclonal antibody (B01) (H00003553-B01). -
Gene Info — IL1B
Entrez GeneID
3553GeneBank Accession#
NM_000576Protein Accession#
AAH08678.1Gene Name
IL1B
Gene Alias
IL-1, IL1-BETA, IL1F2
Gene Description
interleukin 1, beta
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq
Other Designations
catabolin|preinterleukin 1 beta|pro-interleukin-1-beta
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Interactome
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Disease
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