FCER2 (Human) Recombinant Protein (P01)
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Specification
Product Description
Human FCER2 full-length ORF ( AAH14108, 1 a.a. - 321 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MEEGQYSEIEELPRRRCCRRGTQIVLLGLVTAALWAGLLTLLLLWHWDTTQGLKQLEERAARNVSQVSKNLESHHGDQMAQKSQSTQISQELEELRAEQQRLKSQDLELSWNLNGLQADLSSFKSQELNERNEASDLLERLREEVTKLRMELQVSSGFVCNTCPEKWINFQRKCYYFGKGTKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHVDYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDRLATCTPPASEGSAESMGPDSRPDPDGRLPTPSAPLHS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
61.05
Interspecies Antigen Sequence
Mouse (54); Rat (55)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — FCER2
Entrez GeneID
2208GeneBank Accession#
BC014108Protein Accession#
AAH14108Gene Name
FCER2
Gene Alias
CD23, CD23A, CLEC4J, FCE2, IGEBF
Gene Description
Fc fragment of IgE, low affinity II, receptor for (CD23)
Omim ID
151445Gene Ontology
HyperlinkGene Summary
The human leukocyte differentiation antigen CD23 (FCE2) is a key molecule for B-cell activation and growth. It is the low-affinity receptor for IgE. The truncated molecule can be secreted, then functioning as a potent mitogenic growth factor.[supplied by OMIM
Other Designations
C-type lectin domain family 4, member J|CD23 antigen|Fc fragment of IgE, low affinity II, receptor for (CD23A)
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Interactome
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Pathway
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Disease
- Asthma
- Birth Weight
- Bronchiolitis
- Genetic Predisposition to Disease
- Glioblastoma
- Glioma
- Infant
- Leukemia
- Lung Neoplasms
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