DRD2 monoclonal antibody (M01A), clone 1B11
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant DRD2.
Immunogen
DRD2 (AAH21195, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIF
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Rat (96)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.73 KDa) .
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
DRD2 monoclonal antibody (M01A), clone 1B11 Western Blot analysis of DRD2 expression in HL-60 ( Cat # L014V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — DRD2
Entrez GeneID
1813GeneBank Accession#
BC021195Protein Accession#
AAH21195Gene Name
DRD2
Gene Alias
D2DR, D2R
Gene Description
dopamine receptor D2
Gene Ontology
HyperlinkGene Summary
This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq
Other Designations
dopamine receptor D2 isoform|seven transmembrane helix receptor
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Interactome
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Pathway
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Disease
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Publication Reference
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SCH23390, a dopamine D(1) receptor antagonist, suppressed scratching behavior induced by compound 48/80 in mice.
Akimoto Y, Furuse M.
European Journal of Pharmacology 2011 Nov; 670(1):162.
Application:IF, Mouse, Mouse lateral hypothalamus.
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SCH23390, a dopamine D(1) receptor antagonist, suppressed scratching behavior induced by compound 48/80 in mice.
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