CTLA4 (Human) Matched Antibody Pair
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Specification
Product Description
This antibody pair set comes with a matched antibody pair to detect and quantify the protein level of human CTLA4.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (67%); Rat (68%)
Quality Control Testing
Standard curve using mammalian expressed recombinant protein as an analyte.
Sandwich ELISA detection sensitivity ranging from 0.1 ng/ml to 100 ng/ml.
Supplied Product
Antibody pair set content:
1. Capture antibody: mouse monoclonal anti-CTLA4, IgG1 Kappa (100 ug)
2. Detection antibody: biotinylated mouse monoclonal anti-CTLA4, IgG1 Kappa (50 ug)
*Reagents are sufficient for at least 3-5 x 96 well plates using recommended protocols.Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
ELISA Pair (Recombinant protein)
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Gene Info — CTLA4
Entrez GeneID
1493Gene Name
CTLA4
Gene Alias
CD152, CELIAC3, CTLA-4, GSE, IDDM12
Gene Description
cytotoxic T-lymphocyte-associated protein 4
Gene Ontology
HyperlinkGene Summary
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq
Other Designations
OTTHUMP00000163781|cytotoxic T-lymphocyte-associated antigen 4|cytotoxic T-lymphocyte-associated serine esterase-4|ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4
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Interactome
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Pathway
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Disease
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Publication Reference
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Serum sCTLA-4 levels and clinical manifestations in ankylosing spondylitis patients.
Çetintepe SP, Şentürk T, Sargın G, Aydın N.
European Journal of Rheumatology 2018 Jul; 5(2):115.
Application:Quant, Human, Human serum.
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Serum sCTLA-4 levels and clinical manifestations in ankylosing spondylitis patients.
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