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- Home > Products > MaxPab® Ab > Human > Neurobiology > TPP1 MaxPab mouse polyclonal antibody (B01)
TPP1 MaxPab mouse polyclonal antibody (B01) 
- Catalog # : H00001200-B01
- Visit Frequency :
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- 50 uL
- USD $ 319
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Phone : +1-909-992-0619 (new)
Fax : +1-909-992-3401- Products will be shipped directly to the customer.
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human TPP1 protein.
- Immunogen:
- TPP1 (NP_000382, 1 a.a. ~ 563 a.a) full-length human protein.
- Sequence:
- MGLQACLLGLFALILSGKCSYSPEPDQRRTLPPGWVSLGRADPEEELSLTFALRQQNVERLSELVQAVSDPSSPQYGKYLTLENVADLVRPSPLTLHTVQKWLLAAGAQKCHSVITQDFLTCWLSIRQAELLLPGAEFHHYVGGPTETHVVRSPHPYQLPQALAPHVDFVGGLHRFPPTSSLRQRPEPQVTGTVGLHLGVTPSVIRKRYNLTSQDVGSGTSNNSQACAQFLEQYFHDSDLAQFMRLFGGNFAHQASVARVVGQQGRGRAGIEASLDVQYLMSAGANISTWVYSSPGRHEGQEPFLQWLMLLSNESALPHVHTVSYGDDEDSLSSAYIQRVNTELMKAAARGLTLLFASGDSGAGCWSVSGRHQFRPTFPASSPYVTTVGGTSFQEPFLITNEIVDYISGGGFSNVFPRPSYQEEAVTKFLSSSPHLPPSSYFNASGRAYPDVAALSDGYWVVSNRVPIPWVSGTSASTPVFGGILSLINEHRILSGRPPLGFLNPRLYQQHGAGLFDVTRGCHESCLDEEVEGQGFCSGPGWDPVTGWGTPNFPALLKTLLNP
- Host:
- Mouse
- Reactivity:
- Human
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- Storage Buffer:
- No additive
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Note:
- For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
- MSDS:
Download
- Applications
- Western Blot (Tissue lysate)
- TPP1 MaxPab polyclonal antibody. Western Blot analysis of TPP1 expression in human spleen.
- Protocol Download
- Western Blot (Cell lysate)
- TPP1 MaxPab polyclonal antibody. Western Blot analysis of TPP1 expression in Jurkat.
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of TPP1 expression in transfected 293T cell line (H00001200-T01) by TPP1 MaxPab polyclonal antibody.
Lane 1: TPP1 transfected lysate(61.93 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of purified MaxPab antibody to TPP1 on formalin-fixed paraffin-embedded human spleen. [antibody concentration 3 ug/ml]
- Protocol Download
- Entrez GeneID:
- 1200
- GeneBank Accession#:
- NM_000391
- Protein Accession#:
- NP_000382
- Gene Name:
- TPP1
- Gene Alias:
- CLN2,GIG1,LPIC,MGC21297
- Gene Description:
- tripeptidyl peptidase I
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq
- Other Designations:
- ceroid-lipofuscinosis, neuronal 2, late infantile (Jansky-Bielschowsky disease),growth-inhibiting protein 1,lysosomal pepstatin insensitive protease,tripeptidyl aminopeptidase,tripeptidyl-peptidase I
- Gene Pathway
- Related Disease
