AKR1C4 (Human) IP-WB Antibody Pair
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More Files
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Immunoprecipitation of AKR1C4 transfected lysate using rabbit polyclonal anti-AKR1C4 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse polyclonal anti-AKR1C4.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of AKR1C4 transfected lysate using rabbit polyclonal anti-AKR1C4 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse polyclonal anti-AKR1C4.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-AKR1C4 (300 ul)
2. Antibody pair for WB: mouse polyclonal anti-AKR1C4 (50 ul)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — AKR1C4
Entrez GeneID
1109Gene Name
AKR1C4
Gene Alias
3-alpha-HSD, C11, CDR, CHDR, DD4, HAKRA, MGC22581
Gene Description
aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)
Omim ID
600451Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq
Other Designations
3 alpha-hydroxysteroid dehydrogenase/dihydrodiol dehydrogenase 4|OTTHUMP00000018997|aldo-keto reductase family 1, member C4|chlordecone reductase|dihydrodiol dehydrogenase 4|dihydrodiol dehydrogenase isozyme DD4|type I 3-alpha-hydroxysteroid dehydrogenase
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Interactome
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Pathway
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Disease
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