AKR1C4 MaxPab mouse polyclonal antibody (B01)
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More Files
- More Functions
Western Blot (Tissue lysate)
AKR1C4 MaxPab polyclonal antibody. Western Blot analysis of AKR1C4 expression in human liver.
Western Blot (Transfected lysate)
Western Blot analysis of AKR1C4 expression in transfected 293T cell line (H00001109-T01) by AKR1C4 MaxPab polyclonal antibody.
Lane 1: AKR1C4 transfected lysate(35.53 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human AKR1C4 protein.
Immunogen
AKR1C4 (AAH20744.1, 1 a.a. ~ 323 a.a) full-length human protein.
Sequence
MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDFLMDHPDYPFSDEY
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Tissue lysate)
AKR1C4 MaxPab polyclonal antibody. Western Blot analysis of AKR1C4 expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of AKR1C4 expression in transfected 293T cell line (H00001109-T01) by AKR1C4 MaxPab polyclonal antibody.
Lane 1: AKR1C4 transfected lysate(35.53 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — AKR1C4
Entrez GeneID
1109GeneBank Accession#
BC020744.1Protein Accession#
AAH20744.1Gene Name
AKR1C4
Gene Alias
3-alpha-HSD, C11, CDR, CHDR, DD4, HAKRA, MGC22581
Gene Description
aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)
Omim ID
600451Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq
Other Designations
3 alpha-hydroxysteroid dehydrogenase/dihydrodiol dehydrogenase 4|OTTHUMP00000018997|aldo-keto reductase family 1, member C4|chlordecone reductase|dihydrodiol dehydrogenase 4|dihydrodiol dehydrogenase isozyme DD4|type I 3-alpha-hydroxysteroid dehydrogenase
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Interactome
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Pathway
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Disease
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