CD74 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human CD74 full-length ORF ( AAH24272, 1 a.a. - 160 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MHRRRSRSCREDQKPVMDDQRDLISNNEQLPMLGRRPGAPESKCSRGALYTGFSILVTLLLAGQATTAYFLYQQQGRLDKLTVTSQNLQLENLRMKLPKPPKPVSKMRMATPLLMQALPMGALPQGPMQNATKYGNMTEDHVMHLLQSHWNWRTRLLGWV
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
43.34
Interspecies Antigen Sequence
Mouse (78); Rat (79)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CD74
Entrez GeneID
972GeneBank Accession#
BC024272Protein Accession#
AAH24272Gene Name
CD74
Gene Alias
DHLAG, HLADG, Ia-GAMMA
Gene Description
CD74 molecule, major histocompatibility complex, class II invariant chain
Omim ID
142790Gene Ontology
HyperlinkGene Summary
major histocompatibility complex
Other Designations
CD74 antigen|CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)|HLA-DR-gamma|Ia-associated invariant chain|MHC HLA-DR gamma chain|gamma chain of class II antigens
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Interactome
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Pathway
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Disease
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Publication Reference
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Diagnostic value of anti-CD74 antibodies in early and late axial spondyloarthritis and its relationship to disease activity.
Marwa Mahmoud Abdelaziz, Rania M Gamal, Nadia M Ismail, Raghda A Lafy, Helal F Hetta.
Rheumatology (Oxford, England) 2020 Jul; awaa145.
Application:ELISA, As a standard.
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Autoantibodies against CD74 in spondyloarthritis.
Baerlecken NT, Nothdorft S, Stummvoll GH, Sieper J, Rudwaleit M, Reuter S, Matthias T, Schmidt RE, Witte T.
Annals of the Rheumatic Diseases 2014 Jun; 73(6):1211.
Application:ELISA, Human, Serum.
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Diagnostic value of anti-CD74 antibodies in early and late axial spondyloarthritis and its relationship to disease activity.
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