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- Home > Products > siRNA/Chimera > Pre-design Chimera > Apoptosis > CD28 Pre-design Chimera RNAi
CD28 Pre-design Chimera RNAi
- Catalog # : H00000940-R02
- Visit Frequency :
- Size
- Price
- In Stock
- Availability
- Cart
- 10 nmol
- USD $ 239
- order now, ship in 2 weeks
-
- 20 nmol
- USD $ 289
- order now, ship in 2 weeks
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- The price is valid only in USA. Please select country.
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Email : sales@abnova.com
Phone : +1-909-992-0619 (new)
Fax : +1-909-992-3401- Products will be shipped directly to the customer.
- Specification
- Product Description:
- Homo sapiens CD28 antigen (Tp44) (CD28), mRNA.
- Reactivity:
- Human
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_006139
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Note:
- Position of the Chimera RNAi.
-
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 940
- Gene Name:
- CD28
- Gene Alias:
- MGC138290,Tp44
- Gene Description:
- CD28 molecule
- Omim ID:
- 186760
- Gene Ontology:
- Hyperlink
- Gene Summary:
- CD28 costimulation is essential for CD4 (MIM 186940)-positive T-cell proliferation, survival, interleukin-2 (IL2; MIM 147680) production, and T-helper type-2 (Th2) development.[supplied by OMIM
- Other Designations:
- CD28 antigen,CD28 antigen (Tp44),T-cell-specific surface glycoprotein
- Related Disease
- Acute Disease
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Behcet Syndrome
- Bronchiolitis, Viral
- Carcinoma, Squamous Cell
- Celiac Disease
- Cholangitis, Sclerosing
- Colon cancer
- Colorectal Neoplasms
- Diabetes Mellitus, Type 1
- Disease Progression
- Drug Eruptions
- Genetic Predisposition to Disease
- Hematologic Diseases
- Hepatitis C
- Hodgkin Disease
- Hypersensitivity, Immediate
