BMP5 monoclonal antibody (M30C), clone 4A3
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant BMP5.
This product is belong to Cell Culture Grade Antibody (CX Grade).Immunogen
BMP5 (NP_066551.1, 341 a.a. ~ 454 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
VGDYNTSEQKQACKKHELYVSFRDLGWQDWIIAPEGYAAFYCDGECSFPLNAHMNATNHAIVQTLVHLMFPDHVPKPCCAPTKLNAISVLYFDDSSNVILKKYRNMVVRSCGCH
Host
Mouse
Reactivity
Human
Preparation Method
Cell Culture Production
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In condensed culture supernatant
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
ELISA
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Gene Info — BMP5
Entrez GeneID
653GeneBank Accession#
NM_021073.1Protein Accession#
NP_066551.1Gene Name
BMP5
Gene Alias
MGC34244
Gene Description
bone morphogenetic protein 5
Omim ID
112265Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. This protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. This gene is differentially regulated during the formation of various tumors. [provided by RefSeq
Other Designations
OTTHUMP00000016650
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Interactome
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Disease
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