APRT/CEN16q FISH Probe
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Hybridization position of the probes on the chromosome:
Hybridization position of the probes on the chromosome:
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Specification
Product Description
Labeled FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology).
Probe 1
Name: APRT
Size: Approximately 330kb
Fluorophore: Texas Red
Location: 16q24.3Probe 2
Name: CEN16q
Size: Approximately 700kb
Fluorophore: FITC
Location: 16q12.1Probe Gap
The gap between two probes is approximately 39,000 kb.
Origin
Human
Source
Genomic DNA
Reactivity
Human
Form
Liquid
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Regulation Status
For research use only (RUO)
Quality Control Testing
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Supplied Product
DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe
Storage Instruction
Store at 4°C in the dark.
Note
Hybridization position of the probes on the chromosome:
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Applications
Fluorescent In Situ Hybridization (Cell)
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Gene Info — APRT
Entrez GeneID
353Gene Name
APRT
Gene Alias
AMP, DKFZp686D13177, MGC125856, MGC125857, MGC129961
Gene Description
adenine phosphoribosyltransferase
Omim ID
102600Gene Ontology
HyperlinkGene Summary
Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
AMP diphosphorylase|AMP pyrophosphorylase|adenine phosphoribosyltransferase, isoform a|transphosphoribosidase
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Interactome
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Pathway
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